We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
Read More
7
Vitamin D's role in sleep apnea
Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea.
We explored the connection between vitamin D levels and obstructive sleep apnea (OSA) severity in a group of 262 adults who were diagnosed with OSA through polysomnography (a type of sleep study). Our aim was to understand if vitamin D deficiency could influence the severity of sleep apnea symptoms, particularly given the growing evidence linking these two health issues.
In our findings, we observed that 63% of participants had low vitamin D levels, which were associated with increased severity of OSA. The results showed a negative correlation between vitamin D levels and key sleep parameters, meaning that lower vitamin D was linked to worse apnea-hypopnea indices, which measure the frequency of breathing interruptions.
Notably, when we adjusted for various factors like age, sex, and body mass index, our analysis revealed that individuals with higher vitamin D levels had lower chances of experiencing severe OSA. Conversely, those with vitamin D deficiency were nearly three times more likely to have severe symptoms, particularly in individuals over 50 or those categorized as obese.
This study suggests that maintaining adequate vitamin D levels might be important in managing OSA severity. However, it’s essential to note that we did not specifically examine the effects of vitamin D treatment, so more research is needed to determine whether increasing vitamin D can effectively improve sleep apnea outcomes.
Overall, our work highlights the potential role of vitamin D as a modifiable factor in the complex management of obstructive sleep apnea and its symptoms.
Read More
7
Vitamin D and sleep apnea explored
Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review.
We delved into the intriguing link between vitamin D deficiency and obstructive sleep apnea (OSA). Our investigation revealed that many individuals with OSA also struggle with low vitamin D levels, no matter where they are located around the globe. This finding suggests that there may be underlying factors contributing to vitamin D deficiency beyond just insufficient sunlight exposure.
Furthermore, we observed that reduced levels of vitamin D might correlate with more severe cases of OSA. This led us to consider whether boosting vitamin D levels through supplementation could serve as a potential treatment for OSA. Notably, some studies pointed out that patients who took vitamin D supplements reported improvements in sleep quality and a decrease in the severity of their OSA symptoms.
We proposed several potential mechanisms for how vitamin D might influence OSA. These included its role in reducing inflammation and oxidative stress, improving immune function, affecting muscle function, and even involving genetic factors related to vitamin D receptors. However, we underline the need for further research to better understand these connections and to figure out the best dosages and treatment durations for vitamin D supplementation.
Read More
Most Useful Reviews
7.5
Nail growth observed
1 people found this helpful
Best calcium and magnesium supplement! I’ve tried various calcium supplements, but this one works best for me. While using it, I noticed my nails grew long for the first time, and it helped me sleep easily at night with a calming effect. Despite criticisms of coral calcium, I personally find it complements my body chemistry, likely due to the trace minerals in coral reefs.
Read More
7.5
Quality of sleep
Very good! It is helpful for sleep. I take one before bed, and I've noticed an improvement in sleep quality. I will continue taking it.
Read More
6
Enhanced relaxation
2 people found this helpful
Interesting product! I am very pleased with the quality. I sleep well if one capsule is taken an hour or two before bedtime with a small meal. A small amount of magnesium is relaxing and aids in better sleep. However, too much magnesium negatively impacts sleep, making it uncomfortable.
We embarked on an intriguing study to see how an eight-week weight loss and lifestyle intervention could influence vitamin D levels in men suffering from obstructive sleep apnea (OSA). Our group of 89 men was split into two; one group received usual care, while the second group engaged in the lifestyle program alongside their standard treatment.
After this intervention, we observed some promising results regarding vitamin D levels. Specifically, the intervention group showed a significant increase in serum 25-hydroxyvitamin D (25(OH)D) levels, with improvements noted at both the end of the 8 weeks and six months later. Indeed, their vitamin D deficiency was potentially resolved.
Moreover, we found that these higher vitamin D levels correlated with better sleep quality, as evidenced by increased sleep efficiency and improvements in several sleep metrics, such as the apnea-hypopnea index (AHI) and oxygen desaturation index. Additionally, body composition measurements, including fat mass, also showed positive changes.
In conclusion, our findings suggest that a coordinated approach combining weight loss and lifestyle changes can be beneficial not just for vitamin D status, but also for overall health aspects related to obstructive sleep apnea.
Read More
8
Vitamin D may reduce OSA risk
Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea.
We embarked on a large-scale study to understand how vitamin D influences obstructive sleep apnea (OSA), especially in those who are obese. Analyzing data from nearly 445,000 participants from the UK Biobank, we focused on individuals who had no previous diagnosis of OSA. The key outcome was the development of new cases of OSA over an average follow-up of 12 years.
What we found was intriguing: higher serum levels of 25-hydroxyvitamin D, the main form of vitamin D in the bloodstream, were associated with a reduced risk of developing new-onset OSA, particularly in participants struggling with obesity. Those with both a body mass index (BMI) of 25 or higher and waist circumference measurements of 90 cm or more showed a significant inverse relationship. This suggests that those with these characteristics might benefit more from maintaining higher vitamin D levels.
The results indicate that while vitamin D supplementation on its own wasn't tested, our findings certainly highlight its potential role in preventing OSA, particularly in at-risk populations. It's a reminder of the importance of monitoring and maintaining adequate vitamin D levels, especially for those dealing with obesity.
Read More
7
Vitamin D3 aids OSA treatment
Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients.
We conducted a study aimed at understanding how vitamin D3 might influence obstructive sleep apnea (OSA), particularly in hypertensive, obese patients. The research carefully examined the potential benefits of combining vitamin D3 with a medication called Dapagliflozin, a type of SGLT-2 inhibitor known for its additional cardiovascular advantages.
Over 16 weeks, participants were divided into four groups: those receiving Dapagliflozin, those receiving vitamin D3, those receiving both treatments, and a control group that received no treatment. We looked at a range of health parameters, including weight, blood sugar levels, and quality of life scores, to assess the overall impact of these treatments.
Our findings revealed positive outcomes from using vitamin D3 alongside SGLT-2 inhibitors, suggesting that this combination therapy could help improve cardiac and metabolic health, as well as quality of life in patients struggling with OSA. However, we acknowledged the need for further studies to isolate the specific effects of vitamin D on sleep apnea independently from the benefits provided by the medication.
Read More
7
Vitamin D's role in sleep apnea
Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea.
We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
Read More
7
Vitamin D and sleep apnea explored
Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review.
We delved into the intriguing link between vitamin D deficiency and obstructive sleep apnea (OSA). Our investigation revealed that many individuals with OSA also struggle with low vitamin D levels, no matter where they are located around the globe. This finding suggests that there may be underlying factors contributing to vitamin D deficiency beyond just insufficient sunlight exposure.
Furthermore, we observed that reduced levels of vitamin D might correlate with more severe cases of OSA. This led us to consider whether boosting vitamin D levels through supplementation could serve as a potential treatment for OSA. Notably, some studies pointed out that patients who took vitamin D supplements reported improvements in sleep quality and a decrease in the severity of their OSA symptoms.
We proposed several potential mechanisms for how vitamin D might influence OSA. These included its role in reducing inflammation and oxidative stress, improving immune function, affecting muscle function, and even involving genetic factors related to vitamin D receptors. However, we underline the need for further research to better understand these connections and to figure out the best dosages and treatment durations for vitamin D supplementation.
Best calcium and magnesium supplement! I’ve tried various calcium supplements, but this one works best for me. While using it, I noticed my nails grew long for the first time, and it helped me sleep easily at night with a calming effect. Despite criticisms of coral calcium, I personally find it complements my body chemistry, likely due to the trace minerals in coral reefs.
Read More
7.5
Quality of sleep
Very good! It is helpful for sleep. I take one before bed, and I've noticed an improvement in sleep quality. I will continue taking it.
Read More
6
Enhanced relaxation
2 people found this helpful
Interesting product! I am very pleased with the quality. I sleep well if one capsule is taken an hour or two before bedtime with a small meal. A small amount of magnesium is relaxing and aids in better sleep. However, too much magnesium negatively impacts sleep, making it uncomfortable.
Read More
9
Bone health support
Good! I consistently take it for both bone health and a good night's sleep.
Read More
Frequently Asked Questions
Sleep apnea is a common and potentially serious sleep disorder characterized by irregular breathing patterns during sleep. Individuals with sleep apnea experience episodes of disrupted or paused breathing, which can occur multiple times throughout the night. These interruptions can last a few seconds to several minutes and often lead to fragmented sleep, which may result in excessive daytime sleepiness, irritability, and difficulty concentrating. The condition can be broadly classified into two main types: obstructive sleep apnea (OSA), caused by a blockage of the upper airway, and central sleep apnea (CSA), which occurs when the brain fails to send the proper signals to the muscles that control breathing.
The diagnosis of sleep apnea typically involves a sleep study, either conducted in a sleep clinic or at home using portable monitoring devices. Treatment options vary depending on the severity of the condition but may include lifestyle changes, the use of continuous positive airway pressure (CPAP) machines, oral appliances, or even surgery in some cases. If left untreated, sleep apnea can lead to various health complications, including cardiovascular issues, metabolic disorders, and impaired cognitive function, making it essential to consult a healthcare professional if you suspect you or someone you know may be affected by this disorder.
Coral calcium is a dietary supplement derived from coral reefs, primarily harvested from marine environments. It contains a blend of calcium and magnesium, along with trace minerals that are also found in the ocean. The idea behind using coral calcium as a supplement is that it provides a natural source of these essential minerals, which are important for maintaining bone health, muscle function, and overall wellness. Proponents of coral calcium argue that it offers superior absorption compared to other forms of calcium, although scientific evidence supporting these claims is mixed.
It is worth noting that the sustainability and environmental impact of harvesting coral calcium has raised concerns among environmentalists. The extraction process can be harmful to coral ecosystems, which are already threatened by climate change and pollution. As with any supplement, it is crucial to consult with a healthcare professional before adding coral calcium to your routine. They can provide personalized advice based on your dietary needs and health goals, ensuring you choose the right form of supplementation for your lifestyle.
Based on user reviews, the time it typically takes to see results from this calcium and magnesium supplement can vary. While some users mention immediate benefits, such as improved sleep quality after just one dose taken an hour before bedtime Read Review, others report consistent use leading to better sleep over time Read Review.
Additionally, one user noted that they experienced calming effects that helped them sleep easily at night while using the supplement, indicating that positive changes can occur relatively quickly Read Review. Overall, it seems that users have seen improvements in sleep quality either shortly after starting the supplement or with regular use, suggesting that results can be evident quickly for some, while others may see gradual benefits.
The use of vitamin D as a supplement for managing obstructive sleep apnea (OSA) is gaining interest in the scientific community, with several studies suggesting a potential benefit. Research shows that lower vitamin D levels are correlated with increased severity of OSA symptoms, such as higher apnea-hypopnea indices and lower oxygen saturation during sleep[3][5]. Furthermore, interventions to improve vitamin D levels through weight loss and lifestyle changes have indicated improvements in sleep quality and a reduction in apnea metrics[2].
However, while the association between low vitamin D levels and OSA severity is evident, the direct effects of vitamin D supplementation on improving OSA symptoms require more rigorous investigation. Current findings suggest that maintaining adequate vitamin D levels may play a role in managing OSA severity, particularly in individuals with obesity[6]. Overall, while there is promising evidence supporting vitamin D's potential benefits for OSA, definitive conclusions regarding its supplementation as a treatment option are still under research.
Users have reported a range of positive improvements in symptoms after incorporating this calcium and magnesium supplement into their routines. Many individuals have noted significant enhancements in sleep quality, suggesting that the supplement effectively promotes better rest. For instance, one user shared that they experienced not only improved sleep but also a calming effect, which helped them transition into slumber more easily Read Review. Another reviewer echoed this sentiment, stating that taking a capsule before bedtime led to noticeable improvements in how restful their sleep was Read Review.
In addition to sleep enhancements, some users have observed other benefits, such as healthier nails and overall well-being, which seem to stem from the supplement's unique composition, including trace minerals Read Review. While individual results may vary due to personal body chemistry and dosage, frequent users of the supplement report feeling satisfied with its contributions to both sleep quality and bone health, underscoring its dual purpose as a wellness aid Read Review.
Users report that Coral Calcium can be effective for improving sleep quality when taken in the right dosage. Many reviews suggest that a single capsule taken before bed may help enhance sleep, with one user specifically noting the positive impact of taking one capsule an hour or two before sleep, especially when accompanied by a small meal Read Review. Another user echoed this sentiment, mentioning that they take one capsule before bedtime and have experienced noticeable improvements in their sleep quality Read Review.
However, users also caution that too much magnesium can have adverse effects on sleep, suggesting that moderation is key Read Review. Overall, while individual experiences may vary, it appears that users generally recommend taking Coral Calcium in small doses, particularly one capsule, for a relaxing effect that aids in better sleep.
6
Enhanced relaxation
2 people found this helpful
Interesting product! I am very pleased with the quality. I sleep well if one capsule is taken an hour or two before bedtime with a small meal. A small amount of magnesium is relaxing and aids in better sleep. However, too much magnesium negatively impacts sleep, making it uncomfortable.
9
Bone health support
Good! I consistently take it for both bone health and a good night's sleep.
7.5
Nail growth observed
1 people found this helpful
Best calcium and magnesium supplement! I’ve tried various calcium supplements, but this one works best for me. While using it, I noticed my nails grew long for the first time, and it helped me sleep easily at night with a calming effect. Despite criticisms of coral calcium, I personally find it complements my body chemistry, likely due to the trace minerals in coral reefs.
7.5
Quality of sleep
Very good! It is helpful for sleep. I take one before bed, and I've noticed an improvement in sleep quality. I will continue taking it.
7
Vitamin D's role in sleep apnea
Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea.
We aimed to explore the connection between Vitamin D levels and excessive daytime sleepiness in patients diagnosed with obstructive sleep apnea (OSA). In this study, we analyzed serum Vitamin D levels in a group of newly diagnosed OSA patients, dividing them into two categories: those who experienced excessive daytime sleepiness (EDS) and those who did not.
Our findings indicated that patients with EDS had significantly lower levels of Vitamin D compared to their non-somnolent counterparts. The study showed that lower Vitamin D levels correlated with higher apnea-hypopnea indices (AHI) and lower oxyhemoglobin saturation during sleep. This suggests that sleep-related hypoxia may impact Vitamin D status and contribute to sleepiness.
Moreover, our analysis indicated that lower Vitamin D levels were independent predictors of EDS. This further emphasizes the potential role of Vitamin D in managing sleep quality for these patients. In summary, our study highlights an important association between Vitamin D levels and daytime sleepiness in people with sleep apnea, suggesting that improving Vitamin D status could be beneficial for managing EDS in these individuals.
7
Vitamin D's role in sleep apnea
Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea.
We explored the connection between vitamin D levels and obstructive sleep apnea (OSA) severity in a group of 262 adults who were diagnosed with OSA through polysomnography (a type of sleep study). Our aim was to understand if vitamin D deficiency could influence the severity of sleep apnea symptoms, particularly given the growing evidence linking these two health issues.
In our findings, we observed that 63% of participants had low vitamin D levels, which were associated with increased severity of OSA. The results showed a negative correlation between vitamin D levels and key sleep parameters, meaning that lower vitamin D was linked to worse apnea-hypopnea indices, which measure the frequency of breathing interruptions.
Notably, when we adjusted for various factors like age, sex, and body mass index, our analysis revealed that individuals with higher vitamin D levels had lower chances of experiencing severe OSA. Conversely, those with vitamin D deficiency were nearly three times more likely to have severe symptoms, particularly in individuals over 50 or those categorized as obese.
This study suggests that maintaining adequate vitamin D levels might be important in managing OSA severity. However, it’s essential to note that we did not specifically examine the effects of vitamin D treatment, so more research is needed to determine whether increasing vitamin D can effectively improve sleep apnea outcomes.
Overall, our work highlights the potential role of vitamin D as a modifiable factor in the complex management of obstructive sleep apnea and its symptoms.
9.5
Weight loss improves vitamin D levels
Impact of weight loss and lifestyle intervention on vitamin D in men with obstructive sleep apnea: The INTERAPNEA trial.
We embarked on an intriguing study to see how an eight-week weight loss and lifestyle intervention could influence vitamin D levels in men suffering from obstructive sleep apnea (OSA). Our group of 89 men was split into two; one group received usual care, while the second group engaged in the lifestyle program alongside their standard treatment.
After this intervention, we observed some promising results regarding vitamin D levels. Specifically, the intervention group showed a significant increase in serum 25-hydroxyvitamin D (25(OH)D) levels, with improvements noted at both the end of the 8 weeks and six months later. Indeed, their vitamin D deficiency was potentially resolved.
Moreover, we found that these higher vitamin D levels correlated with better sleep quality, as evidenced by increased sleep efficiency and improvements in several sleep metrics, such as the apnea-hypopnea index (AHI) and oxygen desaturation index. Additionally, body composition measurements, including fat mass, also showed positive changes.
In conclusion, our findings suggest that a coordinated approach combining weight loss and lifestyle changes can be beneficial not just for vitamin D status, but also for overall health aspects related to obstructive sleep apnea.
8
Vitamin D may reduce OSA risk
Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea.
We embarked on a large-scale study to understand how vitamin D influences obstructive sleep apnea (OSA), especially in those who are obese. Analyzing data from nearly 445,000 participants from the UK Biobank, we focused on individuals who had no previous diagnosis of OSA. The key outcome was the development of new cases of OSA over an average follow-up of 12 years.
What we found was intriguing: higher serum levels of 25-hydroxyvitamin D, the main form of vitamin D in the bloodstream, were associated with a reduced risk of developing new-onset OSA, particularly in participants struggling with obesity. Those with both a body mass index (BMI) of 25 or higher and waist circumference measurements of 90 cm or more showed a significant inverse relationship. This suggests that those with these characteristics might benefit more from maintaining higher vitamin D levels.
The results indicate that while vitamin D supplementation on its own wasn't tested, our findings certainly highlight its potential role in preventing OSA, particularly in at-risk populations. It's a reminder of the importance of monitoring and maintaining adequate vitamin D levels, especially for those dealing with obesity.
References
Loh HH, Tay SP, Koa AJ, Yong MC, Said A, et al. Unveiling the benefits of Vitamin D3 with SGLT-2 inhibitors for hypertensive obese obstructive sleep apnea patients. J Transl Med. 2025;23:296. doi:10.1186/s12967-025-06312-w
Vázquez-Lorente H, Herrera-Quintana L, Ruiz JR, Amaro-Gahete FJ, Carneiro-Barrera A. Impact of weight loss and lifestyle intervention on vitamin D in men with obstructive sleep apnea: The INTERAPNEA trial. Sleep Med. 2025;128:37. doi:10.1016/j.sleep.2025.01.011
Archontogeorgis K, Economou NT, Bargiotas P, Nena E, Voulgaris A, et al. Sleepiness and Vitamin D Levels in Patients with Obstructive Sleep Apnea. Healthcare (Basel). 2024;12. doi:10.3390/healthcare12060698
Yao N, Ma C, Dou R, Shen C, Yuan Y, et al. Exploring the link between vitamin D deficiency and obstructive sleep apnea: A comprehensive review. J Sleep Res. 2024;33:e14166. doi:10.1111/jsr.14166
Kechribari I, Kontogianni MD, Georgoulis M, Lamprou K, Perraki E, et al. Associations between Vitamin D Status and Polysomnographic Parameters in Adults with Obstructive Sleep Apnea. Life (Basel). 2024;14. doi:10.3390/life14020275
Zhang Y, Zhang Y, Ye Z, Zhou C, Yang S, et al. Relationship of serum 25-hydroxyvitamin D, obesity with new-onset obstructive sleep apnea. Int J Obes (Lond). 2024;48:218. doi:10.1038/s41366-023-01402-5
Locci C, Ruiu A, Saderi L, Sotgiu G, Bassu S, et al. Relationships between 25-Hydroxyvitamin D Levels and Obstructive Sleep Apnea Severity in Children: An Observational Study. J Clin Med. 2023;12. doi:10.3390/jcm12031242
Luo X, Tang M, Wei X, Peng Y. Association between magnesium deficiency score and sleep quality in adults: A population-based cross-sectional study. J Affect Disord. 2024;358:105. doi:10.1016/j.jad.2024.05.002